Several factors increase the risk of developing BPD, including: - Prematurity: Infants born before 32 weeks of gestation are at higher risk. - Low Birth Weight: Infants weighing less than 1500 grams are more susceptible. - Mechanical Ventilation: Prolonged use of ventilators can damage the delicate lung tissue. - Oxygen Therapy: High concentrations of oxygen can cause oxidative stress and lung injury. - Infections: Prenatal infections and postnatal sepsis can exacerbate lung damage.